CBD In Marijuana May Worsen Glaucoma Raise Eye Pressure: Difference between revisions

<br>One of the most commonly proposed uses of medical marijuana is to treat glaucoma. But a study from researchers at Indiana University has found that a major chemical component in the substance appears to worsen the primary underpinning of the disease: a rise in pressure inside the eye. The chemical that causes this rise in pressure is cannabidiol, or CBD, a non-psychoactive ingredient in cannabis that is increasingly marketed to consumers in products such as oil, gummies, creams and health food. It is also approved in many states as a treatment for conditions such as pediatric epilepsy. The study was reported Dec. 14 in the journal Investigative Ophthalmology & Visual Science. Alex Straiker, an associate scientist in the IU Bloomington College of Arts and Sciences' Department of Psychological and Brain Sciences, who led the study. The study, which was conducted in mice, specifically found that CBD caused an increase in pressure inside the eye of 18 percent for at least four hours after use.<br><br><br><br>Tetrahydrocannabinol, or THC, the primary psychoactive ingredient of marijuana, was found to effectively lower pressure in the eye, as has been previously reported. But the study found that the use of CBD in combination with THC blocked this effect. Specifically, the study found that male mice experienced a drop in eye pressure of nearly 30 percent eight hours after exposure to THC alone. A lower pressure drop of 22 percent was also observed after four hours in male mice. The effect was weaker in female mice. This group experienced a pressure drop of only 17 percent after four hours. No difference in eye pressure was measured after eight hours. The results suggest that females may be less affected by THC, though it isn't clear whether this extends to the substance's psychoactive effects. By comparing the effect of these substances on mice without specific neuroreceptors affected by THC and CBD, the IU researchers were also able to identify the two specific neuroreceptors -- named CB1 and GPR18 -- by which the first substance lowered pressure inside the eye. Materials provided by Indiana University. Note: Content may be edited for style and length. 1. Sally Miller, Laura Daily, Emma Leishman, Heather Bradshaw, Alex Straiker. Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Regulate Intraocular Pressure.<br><br><br><br>While not every bath can be the statement-making bath made popular in the ornate 1980s, every bath can benefit from the flow new bathroom layout ideas. Even baths that can't be enlarged are looking and feeling much better these days, thanks to inventive bathroom accessories, attractive personal touches, appealing color schemes, and intelligent design. Creating a better bath isn't just an indulgence; it's a smart idea. 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